I am a woman without major risk factors. Hypotyroidism has been a problem since my teen years but I continue to take synthroid to help regulate this. I am a walker and very rarely eat foods high in fat. However, I noticed this change in my LDL after menopause. Could this be a factor? I sincerely thank you for replying and will talk to my doc regarding pantothenic acid. I am also going to buy the book for additional tips. Thank you again!