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I am a 51 yr old female and was diagnosed with microvascular coronary artery disease, and then HTN about 5 months ago. I take Ranexa,Norvasc, and Aldactone with HCTZ. I still experince squeezing pains in my left chest, back and left breast and take nitro when this occurs. There are some days that I may take nitro up to 3 or more different times a day, ( one or two pills) is this normal? I think that I am getting to be pre-menopausal and could this be affecting or aggravating what is occuring? Would hormone replacement therapy help with this?